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However, 5-HT 1B/1D (and possibly 5-HT 1F ) receptors are targeted by the antimigraine ‘triptans’, examples of which include sumatriptan and zolmitriptan (which are also used for cluster headaches)
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This segment is led by a duopoly: Novo Nordisk's semaglutide (Ozempic for diabetes, Wegovy for obesity) and Eli Lilly's tirzepatide (Mounjaro for T2D, Zepbound for obesity and sleep apnea) together commanded 57.4% of the overall peptide therapy market in 2026 — an extraordinary concentration in a USD 84.2 billion market
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